KREON 35,000 Ph.Eur.Lipase Units msr.Hard Capsules, 50 pcs

Instructions for use for KREON 35,000 Ph.Eur.Lipase Units msr.Hard Capsules, 50 pcs

Application notes

Adult

1-2 Capsules

3-5 times a day

for the meal

Application areas

Mode of action

How does the ingredient of the medicine work?

The medicine consists of digestive enzymes that are obtained from the pancreas of pigs. These are very similar to the naturally occurring digestive enzymes in the human gastrointestinal tract and mingle with the cheeky porridge after taking the stomach and intestine. There you help to crush the food by splitting the fats, proteins and carbohydrates into smaller units. In this way, the digestion of the food is supported. These are then absorbed into the blood or lymph and distributed via these transport routes into the cells of the individual tissues.

Composition

Contradictions

What speaks against an application?

Always:
- Hypersensitivity to the ingredients

General dosage recommendation:
- Inflammation of the pancreas, in acute condition

What about pregnancy and lactation?
- Pregnancy: Contact your doctor. Various considerations play a role in whether and how the medicine can be used during pregnancy.
- Still -time: According to current knowledge, there is no evidence that the medicine is not used during breastfeeding allowed.

If the medicine has been prescribed to you despite a counter -notification, speak to your doctor or pharmacist. The therapeutic benefit can be higher than the risk of using the application.

Side effects

What adverse effects may occur?

- Gastrointestinal complaints
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Stomach pain
- Super sensitivity reactions of the skin, such as:
- Skin rash
- Allergic reaction
- Sneeze
- Tearing eye
- Narrowing of the respiratory tract

If you notice a disorder or change during treatment, contact your doctor or pharmacist.

For information at this point, side effects are taken into account that occurs in at least one of 1,000 patients treated.

Hints

What should you consider?
- Beware of allergy to pig protein!

Detailed instructions for KREON 35,000 Ph.Eur.Lipase Units msr.Hard Capsules, 50 pcs

Field of use

• What is the drug
  • The drug contains an enzyme mixture, which is called "pancreatic powder.
  • Pancreas powder is also called pancreatin. It supports digestion. The enzymes are obtained from pancreas.
  • The capsules contain small gastric-resistant pellets that slowly release the pancreatic powder into the intestine (gastric-resistant pellets, which are also called minimicrospheres).
• What pancreatin is used for
  • The medicine is used to treat exocrine pancreatic insufficiency. The pancreas does not produce enough enzymes to digest the food. This is often observed in patients
    • with cystic fibrosis, a rare innate disorder
    • with chronic inflammation of the pancreas (chronic pancreatitis)
    • in which the pancreas has been partially or completely removed (partial or total pancreatectomy)
    • with pancreatic cancer
• Pancreatin can be used in children, adolescents and adults. The dosage instructions for the age groups are explained in the "way" category.
• Treatment improves the symptoms of exocrine pancreatic insufficiency, including stool consistency (e.g. fatty stool), abdominal pain, flatulence and stool frequency (diarrhea or constipation), regardless of the underlying disease.
• You should only use this medicine if your doctor has confirmed that you suffer from one of these diseases and your doctor expressly recommended treatment with this product.
• Infants and children may only use this product on the recommendation of a doctor and must be treated under medical supervision.
• If you don't feel better or worse after 5 days, contact your doctor.
• How pancreatin works
  • The enzymes in pancreatine digest the food while walking through the intestine. You should take a pancreatin during or immediately after a meal or snack. This allows the enzymes to mix thoroughly with the food.

Active ingredients / ingredients / ingredients

420 mg pancreas powder (from pig)
35000 Pheur-E Triacylglycerollipase
25200 Pheur-e Amylase
1400 PHEUR-E Proteases
Cetyl alcohol auxiliary material (+)
Dimeticon 1000 Hedge Terms (+)
Iron (II, III) Oxid Hedge substance (+)
Iron (III) hydroxide oxide x-water Hedge substance (+)
Iron (III) oxid auxiliary material (+)
Gelatine auxiliary substance (+)
Hypromellical phthalate Hedge substance (+)
Macrogol 4000 auxiliary substances (+)
Sodium dodecylsulfate auxiliary substance (+)
Titan dioxide HILDBOFT (+)
Triethyl citrat auxiliary substance (+)
23 mg total sodium ion hedge material (+)
Total sodium ion helper (+)

Contradictions

• The medicine must not be taken
  • if you are allergic to the active ingredient or one of the other components of this drug.

dosage

• Take this medicine always exactly as described here or exactly according to your doctor or pharmacist. Ask your doctor or pharmacist if you are not sure.
• Their dosage is measured in "lipase units". Lipase is one of the enzymes in the pancreatic powder. Various strengths of pancreatin contain various amounts of lipase.
• Always follow your doctor's instructions on how much pancreatine you should take.
• Your doctor determines the right dose for you.
• This is based on:
  • the severity of their illness
  • Their weight
  • Their diet
  • the fat content in your chair
• If you continue to have a fat stool or other stomach or intestinal complaints (gastrointestinal symptoms), speak to your doctor because your dosage may have to be adjusted.
• How much pancreatine is to be taken
  • For patients with cystic fibrosis
    • Children:
      • The strength of this drug may not be suitable for initiating therapy in children, depending on the age and weight of the child.
      • The required dose for a child should be determined by the doctor with dosage forms that contain fewer lipase units (e.g. 10,000 or 5,000 lipase units).
      • As soon as the dose has been determined per meal, this strength of the drug can be used in children.
      • The usual initial dose for children under the age of 4 is 1000 lipase units per kilogram of body weight per meal.
      • The usual initial dose for children from 4 years is 500 lipase units per kilogram of body weight per meal.
    • Young people and adults:
      • The weight-based enzyme dose should begin in adolescents and adults with 500 lipase units per kilogram of body weight per meal.
    • For all ages:
      • Your daily total dose should not exceed 2,500 lipase units per meal per kilogram per meal, or 10,000 lipase units per kilogram of body weight per day or 4,000 lipase units per gram of fat intake.
      • For patients with other pancreas
  • For patients with other pancreas
    • Young people and adults:
      • The usual dose for a meal is between 25,000 and 80,000 lipase units.
      • The usual dose for a snack is half of the dose for a meal.

 

• If you have taken a larger amount than you should
  • If you have taken a larger amount of pancreatine than you should, drink a lot of water and speak to your doctor or pharmacist. Very high doses of pancreatic powder have sometimes caused an increase in uric acid in blood (hyperuricaemia) and urine (hyperuricosuria).

 

• If you have forgotten the intake
  • If you have forgotten a dose, take the next dose with the next meal as usual.
  • Do not try to compensate for the forgotten dose.

 

• If you cancel the intake
  • Do not break off without having spoken to your doctor beforehand. Many patients have to take the preparation for the rest of their lives.

Taking

• When is pancreatin to take
  • Always take pancreatine during or immediately after a meal or a snack. This allows the enzymes to mix thoroughly with the food and digest them while it goes through the intestine.
• How can pancreatin be taken?
  • Pancreatin should always be taken together with a meal or a snack.
  • As a whole, the capsules should be swallowed with a little water or juice.
  • Do not crush or chew the capsules or their contents, as this can lead to irritation in the mouth or that can change the mode of action in your body.
  • If it is difficult to swallow the capsules, open them carefully and add the pellets to a small amount of a soft, acid food or acidic liquid. Saure soft dishes can e.g. B. be yogurt or apple sauce. Sour liquids can be apple, orange orr be a pineapple juice. Do not mix the pellets with water, milk, flavored milk, breast milk and baby food or with warm dishes. Swallow the mixture immediately without chopping it or chewing it and drinking some water or juice.
  • Mix in non-acid food or liquid, crush or chew the pellets can lead to irritation in the mouth or change the mode of action in your body.
  • Do not keep the capsules or their contents in your mouth. Make sure that the medicine and the food mixture are completely swallowed and no pellets remain in your mouth.
  • Do not store the mixture.

Patient information

• Warnings and Precautions
  • Please speak to your doctor or pharmacist before taking the preparation.
  • Patients with cystic fibrosis
    • In patients with cystic fibrosis, a rare bowel disease called "fibrosing colonopathy", in which their intestine is narrowed, was reported when taking high-dose pancreatic powder products. Inform your doctor if you suffer from cystic fibrosis and take more than 10,000 lipase units per kilogram of body weight per day and have unusual abdominal difficulties or changes in abdominal symptoms.
    • The dosage of lipase units is explained in the "way" category.
  • Severe allergic reaction
    • When an allergic reaction occurs, end your treatment and speak to your doctor. An allergic reaction could contain itching, hives or rash. In rare cases, a serious allergic reaction with a feeling of warmth, dizziness and fainting, breathing difficulties can occur; These are symptoms of a severe, possibly life -threatening state that is referred to as the "anaphylactic shock". If this is the case, you will immediately call medical help.
    • Before taking your doctor, speak if you are allergic against pig proteins.
  • Review in the mouth
    • Pain in the mouth, irritation (stomatitis), bleeding and ulcer formation in the mouth can occur if the capsules were chewed and/or kept in the mouth for too long. Rinsing the mouth and drinking a glass of water can help when the mouth appears first. Kreon can only be scattered on certain foods.

 

• Wateriness and ability to operate machines
  • Pancreatin has no effect on the traffic and operating machines.

Pregnancy

• If you are pregnant or breastfeed, or if you suspect that you are pregnant or intend to become pregnant, ask your doctor or pharmacist for advice before taking this drug.
• Pregnancy
  • Your doctor will decide whether you can take the preparation during pregnancy.
• Breastfeeding
  • Pancreatin can be used during breastfeeding.

Hints

Manufacturer:  Mylan Healthcare GmbH, Benzstraße 1, 61352 Bad Homburg